- Chemical Name 5alpha-Androstane-3b,17b-diol
- CAS No. 571-20-0
- Contact Us Inquiry
Bulk supply high purity 5alpha-Androstane-3b,17b-diol 571-20-0, Paid sample available
- Molecular Formula: C19H32 O2
- Molecular Weight: 292.462
- Vapor Pressure: 1.27E-08mmHg at 25°C
- Melting Point: 161 °C
- Refractive Index: 1.4709 (estimate)
- Boiling Point: 415°Cat760mmHg
- PKA: 15.07±0.70(Predicted)
- Flash Point: 186°C
- PSA： 40.46000
- Density: 1.09g/cm3
- LogP: 3.75090
5alpha-Androstane-3b,17b-diol(Cas 571-20-0) Usage
|
Definition |
ChEBI: An androstane-3,17-diol that is 5alpha-androstane substituted by beta-hydroxy groups at positions 3 and 17. It is a metabolite of dihydrotestosterone. |
InChI:InChI=1/C19H32O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-17,20-21H,3-11H2,1-2H3/t12-,13-,14-,15-,16-,17-,18-,19-/m0/s1
571-20-0 Relevant articles
One-Step Chemo-, Regio- and Stereoselective Reduction of Ketosteroids to Hydroxysteroids over Zr-Containing MOF-808 Metal-Organic Frameworks
Llabrés i Xamena, F. X.,Mautschke, H.-H.
, p. 10766 - 10775 (2021/06/15)
Zr-containing MOF-808 is a very promisin...
Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells – Identifying inhibitors of non-classical pathways producing the most potent androgen
Boutin, Sophie,Roy, Jenny,Maltais, René,Poirier, Donald
supporting information, (2019/11/26)
5α-Dihydrotestosterone (5α-DHT) possesse...
Role of human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C3) in the extrahepatic metabolism of the steroidal aromatase inactivator Formestane
Wan, Runlan,Kong, Xi,Yang, Youzhe,Tao, Siwen,Chen, Youyou,Teichmann, Alexander Tobias,Wieland, Frank Heinrich
, (2019/12/23)
The clinical use of the steroidal aromat...
A Redox Strategy for Light-Driven, Out-of-Equilibrium Isomerizations and Application to Catalytic C-C Bond Cleavage Reactions
Ota, Eisuke,Wang, Huaiju,Frye, Nils Lennart,Knowles, Robert R.
supporting information, p. 1457 - 1462 (2019/01/25)
We report a general protocol for the lig...
571-20-0 Process route
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![(3S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate](/upload/2026/10/b7323325c1c046b1bafbe0586768016e_51a1207f-e853-4d4a-a7ea-5e407eb81dc7.png)
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3090-70-8
(3S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate
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571-20-0
5-androgen-3,17-diol
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
methanol;
for 0.166667h;
Heating;
|
95%
|
|
With
potassium carbonate;
In
methanol;
at 20 ℃;
for 24h;
Inert atmosphere;
|
89%
|
|
With
sodium hydroxide;
In
methanol;
Yield given;
|
-
-
1239-31-2
3β-acetoxy-5α-androstan-17-one
-
-
571-20-0
5-androgen-3,17-diol
| Conditions | Yield |
|---|---|
|
With
diisobutylaluminium hydride; nickel dichloride;
In
dichloromethane; toluene;
at -78 ℃;
for 0.25h;
Inert atmosphere;
|
99%
|
|
Multi-step reaction
with
2
steps
1: 97 percent / NaBH4
/ methanol / 1 h / 0 - 20 °C
2: 95 percent / NaOH / methanol / 0.17 h / Heating
With
sodium hydroxide; sodium tetrahydroborate;
In
methanol;
|
|
|
Multi-step reaction
with
2
steps
1: sodium tetrahydroborate; methanol / 0.42 h / 20 °C / Inert atmosphere
2: potassium carbonate / methanol / 24 h / 20 °C / Inert atmosphere
With
methanol; sodium tetrahydroborate; potassium carbonate;
In
methanol;
|
571-20-0 Upstream products
-
71-23-8
propan-1-ol
-
481-29-8
Epiandrosterone
-
93-59-4
Perbenzoic acid
-
906-83-2
pregnenolone acetate
571-20-0 Downstream products
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846-46-8
(5α)-androstane-3,17-dione
-
53-41-8
(S)-3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-one
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1229-12-5
androstane-3,17-dione
-
846-46-8
androstanedione