• Chemical Name Chrysophanic acid
  • CAS No. 481-74-3
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What is the Chrysophanic acid ?

Chrysophanic acid is yellow crystalline solid or brown powder, while it's Molecular Formula is C15H10O4. A topical ointment used in the treatment of dermal conditions such as eczema and herpes.

What is the CAS number for Chrysophanic acid ?

The CAS number of Chrysophanic acid is 481-74-3.

More information of Chrysophanic acid 481-74-3 are:

Synonyms

1,8-Dihydroxy-3-methylanthraquinone;9,10-Anthracenedione, 1,8-dihydroxy-3-methyl- (9CI);1,8-dihydroxy-3-methyl-9,10-anthraquinone;C.I. Natural Yellow 23;Anthraquinone, 1,8-dihydroxy-3-methyl-;Chrysophansaeure;9,10-Anthracenedione, 1, 8-dihydroxy-3-methyl-;3-Methyl-1, 8-dihydroxyanthraquinone;9,10-Anthracenedione,1,8-dihydroxy-3- methyl-;

CAS?Number

481-74-3

Molecular Formula

C15H10O4

Molecular Weight

254.242

Density

1.476 g/cm3

Melting Point

194-198 °C

Boiling Point

489.495 °C at 760 mmHg

Flash Point

263.939 °C

HS CODE

29146990

PSA

74.60000

LogP

2.18160

Pka

6.63±0.20(Predicted)

What is Chrysophanic acid (481-74-3) used for?

Chrysophanol is an anthraquinone that has been found in R. palmatum and has diverse biological activities. It induces necrosis in J5 human liver cancer cells when used at concentrations of 25, 50, 75, 100, and 200 μM. Chrysophanol (5, 10, and 50 μM) reduces LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2; ) and inhibits LPS-induced DNA oxidation in BV-2 microglia. In vivo, chrysophanol (5 mg/kg) decreases colonic levels of IL-6 and activation of NF-κB and reduces weight loss, diarrhea, and rectal bleeding in a mouse model of colitis induced by dextran sulfate (DSS; ). Chrysophanol (0.1, 1, and 10 mg/kg) increases survival, reduces brain tissue loss, and ameliorates motor balance deficits in a mouse model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).

InChI:InChI=1/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3

Articles related to Chrysophanic acid:

Article

Source

CONVERSION OF EMODIN TO CHRYSOPHANOL IN A CELL-FREE SYSTEM FROM PYRENOCHAETA TERRESTRIS

Anderson, John A.

, p. 103 - 106 (1986)

A Biomimetic Synthesis of Racemic Dihydroanthracen-1(2H)-ones Using Sodium Borohydride in Water

Mondal, Amit,Singh, Shailesh Kumar,Saha, Nirmal,Husain, Syed Masood

, p. 2425 - 2430 (2020)

How to get the best price on Chrysophanic acid?

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