• Chemical Name DL-SULFORAPHANE
  • CAS No. 4478-93-7
  • Contact Us Inquiry

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1.What is the DL-SULFORAPHANE ?

Sulforaphane is a compound within the isothiocyanate group of organosulfur compounds and mainly found in cruciferous vegetables. It is produced when the enzyme myrosinase transforms glucoraphanin,a prodrug or storage form of SFN, into SFN upon damage to the plant (such as from chewing),which allows the two compounds to mix and react. Glucoraphanin is one of a few molecules known as isothiocyanates, existing alongside Sinigrin (metabolized into allylisothiocyanate).

Potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Occurs naturally in broccoli. It was found to inhibit chemically induced mammary tumor formation in rats. Antitumor agentLNCaP prostate cancer cells were treated with DL-Sulforaphane to study the effect on androgen receptor. Effects on malathion toxicity was studied in rats by treating them with DL-Sulforaphane.Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress.Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1.Because of its protective capabilities, small molecules that activate Nrf2 signaling are being examined as potential anti-cancer or anti-inflammatory agents.Sulforaphane is an isothiocyanate derived from cruciferous vegetables, including broccoli, that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression.At 15 μM, sulforaphane inhibits class I and II HDAC activity and suppresses tumor growth by inducing cell cycle arrest and apoptosis selectively in various cancerous prostate epithelial cells without affecting normal cells.Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

2.What is the CAS number for DL-SULFORAPHANE ?

The CAS number of DL-SULFORAPHANE is 4478-93-7.

More information of DL-SULFORAPHANE 4478-93-7 are:

CAS?Number

4478-93-7

Density

1.17 g/cm3

Boiling Point

368.2 °C at 760 mmHg

Flash Point

176.5 °C

HS CODE

29309090

PSA

80.73000

LogP

2.11360

3.What is the molecular formula of DL-SULFORAPHANE ?

The chemical formula of?DL-SULFORAPHANE is C6H11NOS2 which containing 6 Carbon atoms,11 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 2 Sulfur atoms,and the molecular weight, and the molecular weight of DL-SULFORAPHANE is 177.291

4.What is DL-SULFORAPHANE(4478-93-7)used for?

Sulforaphane is a compound within the isothiocyanate group of organosulfur compounds and mainly found in cruciferous vegetables. It is produced when the enzyme myrosinase transforms glucoraphanin,a prodrug or storage form of SFN, into SFN upon damage to the plant (such as from chewing),which allows the two compounds to mix and react. Glucoraphanin is one of a few molecules known as isothiocyanates, existing alongside Sinigrin (metabolized into allylisothiocyanate).

InChI:InChI=1/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3

Relevant articles related to DL-SULFORAPHANE:

Article

Source

Anti-inflammatory and anti-apoptotic effects of (RS)- glucoraphanin bioactivated with myrosinase in murine sub-acute and acute MPTP-induced Parkinson's disease

Galuppo, Maria,Iori, Renato,De Nicola, Gina Rosalinda,Bramanti, Placido,Mazzon, Emanuela

, p. 5532 - 5547 (2013)

Antioxidant activity of two edible isothiocyanates: Sulforaphane and erucin is due to their thermal decomposition to sulfenic acids and methylsulfinyl radicals

Cedrowski, Jakub,D?browa, Kajetan,Przybylski, Pawe?,Krogul-Sobczak, Agnieszka,Litwinienko, Grzegorz

, (2021/03/30)

5.Manufacturer supply good quality DL-SULFORAPHANE 4478-93-7 with stock

hangzhou xinnongsheng chemicals .,co,ltd. is a quality supplier of DL-SULFORAPHANE. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on DL-SULFORAPHANE 4478-93-7.