- Chemical Name PF 04449913
- CAS No. 1095173-27-5
- Contact Us Inquiry
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1.What is the PF 04449913 ?
PF 04449913 is a small molecule inhibitor that targets the Smoothened (Smo) protein, which plays a crucial role in the Hedgehog signaling pathway. This pathway is involved in various cellular processes, including cell growth, differentiation, and tissue repair. Aberrant activation of the Hedgehog signaling pathway has been associated with several types of cancer, making PF 04449913 a promising pharmaceutical candidate for cancer treatment.
Glasdegib acts as a potent, orally biovailablesmoothened (Smo) inhibitor used in the treatment of cancer.
2.What is the CAS number for PF 04449913 ?
The CAS number of PF 04449913 is 1095173-27-5.
More information of PF 04449913 1095173-27-5 are:
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CAS?Number |
1095173-27-5 |
|
Density |
1.33±0.1 g/cm3(Predicted) |
|
Boiling Point |
633.4±55.0 °C(Predicted) |
|
PSA |
100.33000 |
|
LogP |
3.60688 |
|
Pka |
11.93±0.10(Predicted) |
3.What is the molecular formula of PF 04449913 ?
The chemical formula of?PF 04449913 is C21H22N6O which containing 21 Carbon atoms,22 Hydrogen atoms,6 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight, and the molecular weight of PF 04449913 is 374.445
4.What is PF 04449913(1095173-27-5)used for?
PF 04449913 is a small molecule inhibitor that targets the Smoothened (Smo) protein, which plays a crucial role in the Hedgehog signaling pathway. This pathway is involved in various cellular processes, including cell growth, differentiation, and tissue repair. Aberrant activation of the Hedgehog signaling pathway has been associated with several types of cancer, making PF 04449913 a promising pharmaceutical candidate for cancer treatment.
Relevant articles related to PF 04449913:
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Article |
Source |
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PROCESSES FOR THE PREPARATION OF GLASDEGIB AND SALT THEREOF AND SOLID STATE FORMS OF GLASDEGIB MALEATE AND PROCESS FOR PREPARATION THEREOF |
- Paragraph 00187-00189; 00192; 00197-00199; 00206; 00200, (2021/08/06) |
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